Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes |
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Authors: | Bierne H Sabet C Personnic N Cossart P |
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Institution: | Unité des Interactions Bactéries-Cellules, INSERM U604, INRA USC2020, Institut Pasteur, F-75015 Paris, France. hbierne@pasteur.fr |
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Abstract: | The Listeria monocytogenes genome includes a large family of proteins harbouring leucine-rich repeats known as internalins (Inl). The generation of novel mutants and comparative analysis of Inl variability among Listeria and other bacterial genomes suggest that beyond the extensively-studied invasins, InlA and InlB, additional internalins also play important functions in the infectious process. |
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