Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2) |
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| Authors: | Simon E. Evans |
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| Affiliation: | School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK |
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| Abstract: | |
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| Keywords: | 4&prime -PP, phosphopantetheine ACP, acyl carrier protein act, actinorhodin ACPS, holo acyl carrier protein synthase ARO, aromatase CoA, coenzyme A CYC, cyclase ESMS, electrospray mass spectrometry FAS, fatty acid synthase HSQC, heteronuclear single quantum coherence KR, ketoreductase KSα, ketosynthase KSβ, &lsquo chain length factor&rsquo NOE, nuclear Overhauser enhancement NOESY, nuclear Overhauser enhancement spectroscopy PKS, polyketide synthase TOCSY, total correlated spectroscopy |
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