Chromatid cohesion: acetylation joins the sisters |
| |
| Authors: | Tanaka Koichi Watanabe Yoshinori |
| |
| Institution: | Laboratory of Chromosome Dynamics, Institute of Molecular and Cellular Biosciences, University of Tokyo, Yayoi, Tokyo, Japan. |
| |
| Abstract: | The replication-fork-associated protein Eco1 is required for the establishment of sister chromatid cohesion, which plays an essential role in faithful chromosome segregation. Three recent studies in yeast and humans reveal that the acetyltransferase activity of Eco1 targets the cohesin subunit Smc3 to facilitate the establishment of cohesion. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
