Complete genome sequence of the hemotrophic Mycoplasma suis strain KI3806 |
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| Authors: | Oehlerking Joern Kube Michael Felder Kathrin M Matter Denise Wittenbrink Max M Schwarzenbach Sarah Kramer Manuela M Hoelzle Katharina Hoelzle Ludwig E |
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| Affiliation: | 1Institute of Veterinary Bacteriology, Vetsuisse Faculty, University Zurich, 8057 Zurich, Switzerland;2Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany;3Institute of Environmental and Animal Hygiene and Veterinary Medicine, University Hohenheim, 70599 Stuttgart, Germany |
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| Abstract: | Mycoplasma suis, a member of the hemotrophic mycoplasma (HM) group, parasitize erythrocytes of pigs. Increasing evidence suggests that M. suis is also a zoonotic agent. Highly pathogenic strains of M. suis (e.g., M. suis KI3806) have been demonstrated to invade erythrocytes. This complete sequenced and manually annotated genome of M. suis KI3806 is the first available from this species and from the HM group. The DNA was isolated from blood samples of experimentally infected pigs due to the lack of an in vitro cultivation system. The small circular chromosome of 709,270 bp, encoding an unexpectedly high number of hypothetical proteins and limited transport and metabolic capacities, could reflect the unique lifestyle of HM on the surface of erythrocytes. |
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