Effect of the time of day on central and peripheral fatigue during 2-min maximal voluntary contractions in persons with multiple sclerosis: gender differences |
| |
| Institution: | 1. Department of Urology, Hospital Universitario 12 de Octubre, Madrid, Spain;2. Department of Nephrology and Transplant Coordination, Hospital Universitario 12 de Octubre, Madrid, Spain;1. Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione–University of Pittsburgh Medical Center, Palermo, Italy;2. Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania;1. Department of Surgery, National Chiba-East Hospital, Chiba, Japan;2. National Institute of Radiological Sciences, Chiba, Japan;3. Department of Transplantation Surgery, Fujita Health University, Nagoya, Japan;4. Chiba Ryogo Center, PET Imaging Division, Chiba, Japan;1. Department of Surgery, Division of Abdominal Organ Transplantation, The University of Chicago, Chicago, IL;2. Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China |
| |
| Abstract: | There is a lack of data on fatigue changes within 24 h among patients with multiple sclerosis. The purpose of this study was to evaluate the effect of time of day on central and peripheral fatigue during a continuous 2-min maximal voluntary contraction of the quadriceps muscle in women and men with multiple sclerosis (MS). We studied age-matched MS patients (range, 40–50 years). The inclusion criteria for patients were: a Kurtzke Expanded Disability Status score and a Fatigue Severity Scale score. We found a significant gender difference in central activation ratio (CAR) in the evening. At the end of the 2-min maximal voluntary contraction (MVC), the voluntary torque decreased by about 65% in men and women with MS in both the morning and evening. We also observed that, in women, CAR decreased markedly during the first 30 s in the evening test. The most interesting finding of our study is that central fatigue increased, whereas peripheral fatigue decreased markedly in the evening only in women. It remains unclear why women’s central fatigue is greater in the evening than in the morning. |
| |
| Keywords: | Central and peripheral fatigue Electrical stimulation Gender Morning vs evening Multiple sclerosis |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
