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Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue
Authors:Xiaoyan Hui  Mingliang Zhang  Ping Gu  Kuai Li  Yuan Gao  Donghai Wu  Yu Wang  Aimin Xu
Affiliation:1. State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China;2. Department of Medicine, The University of Hong Kong, Hong Kong, China;3. Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China;4. Department of Endocrinology, School of Medicine, Nanjing University, Nanjing General Hospital of Nanjing Military Command, Nanjing, China;5. CAS Key Laboratory of Regenerative Biology, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China;6. CAS Key Laboratory of Regenerative Biology, Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, China;7. Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China
Abstract:
Keywords:insulin resistance  macrophage infiltration and polarization  metabolic inflammation  obesity  SIRT1
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