Melatonin Biosynthesis in Drosophila: Its Nature and Its Effects |
| |
Authors: | L. Finocchiaro J. Callebert J. M. Launay J. M. Jallon |
| |
Affiliation: | Laboratoire de Biologie et Génétique Evolutives CNRS, Gif sur Yvette, France. |
| |
Abstract: | Drosophila melanogaster homogenates incubated with tritiated 5-hydroxytryptophan, 5-hydroxytryptamine, or N-acetylserotonin have the ability of converting them into labelled indolamines, including melatonin. All these compounds were characterized by two-dimensional thin-layer chromatography by comparison with nonradiolabelled standards, and melatonin by mass spectrometry and radioimmunoassay. On the other hand, the injection of pharmacological doses of melatonin into 2-day-old female flies diminishes the mating speed and the oviposition rate. |
| |
Keywords: | Melatonin Indolamines Drosophila Biosynthesis. |
|
|