Whole body exposure to low frequency magnetic field: No provable effects on the cellular energetics of rat skeletal muscle |
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Authors: | Bohumir Stefl Max Vojtisek Lucie Synecka Jitka Zurmanova |
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Institution: | (1) Department of Physiology and Developmental Biology, Faculty of Science, Charles University, Prague, Czech Republic;(2) National Institute of Public Health, Prague, Czech Republic |
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Abstract: | On the basis of previous experience with biological effects of electromagnetic fields a potential effect of homogeneous sinusoidal
magnetic field (50Hz, 10mT) on energy state of rat skeletal muscle was investigated. Two different total body exposures to
magnetic field were selected: (1) repeated 1 hour exposure, 2 times a week for 3 months, and (2) acute 1.5 hour exposure (and
the appropriate control groups). Important energy metabolites (adenosine triphosphate – ATP, creatine phosphate, creatine,
lactate, pyruvate and inorganic phosphate) were analysed by enzymatic and spectroscopic methods in musculus gracilis cranialis.On the basis of the concentration of important energy metabolites the apparent Gibbs free energy of ATP hydrolysis and creatine
charge was calculated. Our results demonstrate no influence of this low frequency magnetic field on the level of important
energy metabolites in rat skeletal muscle. The conclusion of this study is that neither repeated exposure nor the acute exposure
of rats to the sinusoidal magnetic field of given parameters has any important influence on the energy state of the skeletal
muscle. |
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Keywords: | ATP adenosine-5′ -triphosphate energetics extremely low frequency magnetic field (ELF MF) PCr phosphocreatine skeletal muscle |
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