Key role of calcium signaling in synaptic transmission |
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Authors: | P G Kostyuk |
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Institution: | (1) Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine |
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Abstract: | The review analyzes current concepts on the role of calcium signals in the process of synaptic neuron-to-neuron and neuron-effector
transmission and on the respective intracellular mechanisms (participation of different types of ion channels, mitochondria,
and endoplasmic reticulum). The involvement of calcium both in the transmission per se, in particular in the process of exocytotic neurotransmitter release, and in long-lasting modulations of the efficacy of
synaptic transmission (potentiation or depression) is considered.
Neirofiziologiya/Neurophysiology, Vol. 39, Nos. 4/5, pp. 290–293, July–October, 2007. |
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Keywords: | synaptic transmission calcium signals exocytosis synaptic efficacy |
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