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Modifying interleukin-2 concentrations during culture improves function of T cells for adoptive immunotherapy
Authors:M.J. Besser  E. Schallmach  K. Oved  A.J. Treves  G. Markel  Y. Reiter  J. Schachter
Affiliation:1. Ella Institute of Melanoma, Sheba Medical Center, Tel-Hashomer, Israel;2. Department of Biology, Technion, Haifa, Israel;3. Sheba Cancer Research Center, Sheba Medical Center, Tel-Hashomer, Israel;4. Department of Human Microbiology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel;1. Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA;2. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA;3. Penn SRP Center, Center of Excellence in Environmental Toxicology and Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA;4. A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA;1. Virginia Tech Carilion Research Institute, Roanoke, VA;2. Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA;3. Department of Biomedical Sciences and Pathobiology, Virginia–Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA;4. Virginia Tech Carilion School of Medicine, Roanoke, VA;1. School of Life Sciences, Zhengzhou University, Zhengzhou, China;2. Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China
Abstract:
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