The inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat. |
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| Authors: | I Gross S A Rooney J B Warshaw |
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| Affiliation: | Departments of Pediatrics, Obstetrics and Gynecology and Lung Research Center, Yale University School of Medicine, New Haven, Connecticut, USA |
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| Abstract: | Acute nutritional deprivation results in significant reduction in the activities of acetyl-CoA carboxylase, fatty acid synthetase, microsomal fatty acid elongation and choline phosphotransferase in rat lung. This data establishes the enzymatic basis for the known inhibition of pulmonary surfactant production by acute starvation. |
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