Immune response and potential therapeutic strategies for the SARS-CoV-2 associated with the COVID-19 pandemic |
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Authors: | Xianghui Li Yabo Zhang Libing He Jiangzhe Si Shuai Qiu Yuhua He Jiacun Wei Zhili Wang Longxiang Xie Yanzhang Li Tieshan Teng |
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Affiliation: | 1.Institute of Biomedical Informatics, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.;2.Henan International Joint Laboratory of Nuclear Protein Regulation, School of Basic Medical Science, Henan University, Kaifeng, Henan 475004, China. |
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Abstract: | Following onset of the first recorded case of Coronavirus disease 2019 (COVID-19) in December 2019, more than 269 million cases and over 5.3 million deaths have been confirmed worldwide. COVID-19 is a highly infectious pneumonia, caused by a novel virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, it poses a severe threat to human health across the globe, a trend that is likely to persist in the foreseeable future. This paper reviews SARS-CoV-2 immunity, the latest development of anti-SARS-CoV-2 drugs as well as exploring in detail, immune escape induced by SARS-CoV-2. We expect that the findings will provide a basis for COVID-19 prevention and treatment. |
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Keywords: | COVID-19 SARS-CoV-2 immunity potential drugs |
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