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Immune response and potential therapeutic strategies for the SARS-CoV-2 associated with the COVID-19 pandemic
Authors:Xianghui Li  Yabo Zhang  Libing He  Jiangzhe Si  Shuai Qiu  Yuhua He  Jiacun Wei  Zhili Wang  Longxiang Xie  Yanzhang Li  Tieshan Teng
Affiliation:1.Institute of Biomedical Informatics, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.;2.Henan International Joint Laboratory of Nuclear Protein Regulation, School of Basic Medical Science, Henan University, Kaifeng, Henan 475004, China.
Abstract:Following onset of the first recorded case of Coronavirus disease 2019 (COVID-19) in December 2019, more than 269 million cases and over 5.3 million deaths have been confirmed worldwide. COVID-19 is a highly infectious pneumonia, caused by a novel virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, it poses a severe threat to human health across the globe, a trend that is likely to persist in the foreseeable future. This paper reviews SARS-CoV-2 immunity, the latest development of anti-SARS-CoV-2 drugs as well as exploring in detail, immune escape induced by SARS-CoV-2. We expect that the findings will provide a basis for COVID-19 prevention and treatment.
Keywords:COVID-19   SARS-CoV-2   immunity   potential drugs
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