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Of mitochondrion and COVID-19
Authors:Khalid Omer Alfarouk  Sari T. S. Alhoufie  Abdelhameed Hifny  Laurent Schwartz  Ali S. Alqahtani  Samrein B. M. Ahmed  Ali M. Alqahtani  Saad S. Alqahtani  Abdel Khalig Muddathir  Heyam Ali  Adil H. H. Bashir  Muntaser E. Ibrahim  Maria Raffaella Greco  Rosa A. Cardone  Salvador Harguindey  Stephan Joel Reshkin
Abstract:COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19’s signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19.
Keywords:COVID-19   mitochondrion   inflammation   cytokine storm   treatment
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