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Biosynthesis of Stable Polyshaped Gold Nanoparticles from Microwave-Exposed Aqueous Extracellular Anti-malignant Guava (Psidium guajava) Leaf Extract
Authors:D Raghunandan  S Basavaraja  B Mahesh  S Balaji  S Y Manjunath  A Venkataraman
Institution:2. H.K.E.S’s College of Pharmacy, Sedam Road, Gulbarga, 05, Karnataka, India
3. Veeco-India Nanotechnology Laboratory, Jawaharalal Nehru Cetre for Advanced Scientific Research, Bangalore, 64, India
1. Materials Chemistry Laboratory, Department of Material Science, Gulbarga University, Gulbarga, 585106, Karnataka, India
4. Sri Krupa, Institute of Pharmaceutical Science, Village Velkatta, Siddipeth, Medak, AP, India
Abstract:Addition of microwave-exposed aqueous extracellular anti-malignant guava (Psidium guajava) leaf extract to the aqueous gold chloride solution yielded stable polyshaped gold nanoparticles of high composition. Microwave-assisted route selected for the preparation of aqueous guava leaf extract was to suppress the enzymatic action. The formation of nanoparticles was understood from the UV–visible and X-ray diffraction studies. The size and shape analysis was done using field emission scanning electron microscopy, transmission electron microscopy, and atomic force microscopy. Zeta potential experiment shows that the bio-functionalized gold nanoparticles colloidal solution obtained as above will maintain its stability even after 30 weeks of storage. It is observed that the flavonoids which are separated during microwave heating of extracellular solution of the guava leaves are responsible for the biosynthesis of gold nanoparticles.
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