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Effect of angiotensin II on artificial lipid membranes
Authors:Peter Schlieper
Affiliation:Instituto de Biología Celular, Facultad de Medicina, Universidad de Buenos Aires, 1121 Buenos Aires Argentina
Abstract:(5-Isoleucine)-angiotensin II applied to black lipid membranes produced current fluctuations varying between Δ>G = 5 · 10?11 Ω? and 3.5 · 10?10 Ω?1. These fluctuations depend on the voltage and the hydrostatic pressure. The membrane resistance is lowered by Δ>R = 6.1 · 107 Ω · cm2. With (5-isoleucine, 8-leucine)-angiotensin II the jumps are of a single amplitude (Δ>G = 2 · 10?10 Ω?1). In both cases water and ions are transported across the membrane.
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