Theory of self-assembly of lipid bilayers and vesicles |
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| Authors: | Jacob N. Israelachvili D.John Mitchell Barry W. Ninham |
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| Affiliation: | 1. Department of Applied Mathematics, Research School of Physical Sciences, Institute of Advanced Studies, The Australian National University, Canberra, A.C.T. 2600, Australia;2. Department of Neurobiology, Research School of Biological Sciences, Institute of Advanced Studies, The Australian National University, Canberra, A.C.T. 2600, Australia |
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| Abstract: | A simple theory is developed that explains the formation of bilayers and vesicles and accounts quantitatively for many of their physical properties: Properties including vesicle size distributions and bilayer elasticity emerge from a unified theory that links thermodynamics, interaction free energy, and molelcular geometry. The theory may be applied to the analysis of more complicated membrane structures and mechanisms. |
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