Vancomycin resistance is associated with serine-containing peptidoglycan in Enterococcus gallinarum |
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Authors: | Grohs P Gutmann L Legrand R Schoot B Mainardi J L |
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Affiliation: | Laboratoire de Recherche Moléculaire sur les Antibiotiques, UFR Broussais-H?tel Dieu, Université Paris VI, Paris, France. |
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Abstract: | In Enterococcus gallinarum SC1, a low-level vancomycin-resistant strain, only monomeric muropentapeptides with a C-terminal D-alanine were detected after growth without vancomycin. In contrast, in SC1 induced by vancomycin, as well as in AIB39, a constitutive vancomycin-resistant strain, monomeric and dimeric muropentapeptides with a C-terminal D-serine were detected. |
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