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Vancomycin resistance is associated with serine-containing peptidoglycan in Enterococcus gallinarum
Authors:Grohs P  Gutmann L  Legrand R  Schoot B  Mainardi J L
Institution:Laboratoire de Recherche Moléculaire sur les Antibiotiques, UFR Broussais-H?tel Dieu, Université Paris VI, Paris, France.
Abstract:In Enterococcus gallinarum SC1, a low-level vancomycin-resistant strain, only monomeric muropentapeptides with a C-terminal D-alanine were detected after growth without vancomycin. In contrast, in SC1 induced by vancomycin, as well as in AIB39, a constitutive vancomycin-resistant strain, monomeric and dimeric muropentapeptides with a C-terminal D-serine were detected.
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