Permeabilities of composite membranes containing phospholipids

Two types of artificial membranes containing a phospholipid were prepared and their permeabilities were measured around the phase-transition temperature of the phospholipid. The permeability of the membranes to a hydrophobic solute was higher than to a hydrophilic solute, and showed an abrupt change at the phase-transition temperature of the phospholipid, similar to that in biomembranes and liposomes, caused by the fluidity change of the phospholipid at this temperature.