Treatment of acute ischemic stroke by minimally manipulated umbilical cord-derived mesenchymal stem cells transplantation: A case report |
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Authors: | Hyunjun Ahn Sang Yeon Lee Won Ju Jung Kye-Ho Lee |
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Institution: | Hyunjun Ahn, Sang Yeon Lee, Kye-Ho Lee, bio Beauty&Health Company (bBHC)-Stem Cell Treatment & Research Institute (STRI), Seoul 04420, South KoreaWon Ju Jung, 97.7 Beauty&Health (B&H) Clinics, Seoul 04420, South Korea |
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Abstract: | BACKGROUNDStroke is one of the major causes of disability and death worldwide. Some treatments for stroke exist, but existing treatment methods have limitations such as difficulty in the regeneration of damaged neuronal cells of the brain. Recently, mesenchymal stem cells (MSCs) have been studied as a therapeutic alternative for stroke, and various preclinical and case studies have been reported.CASE SUMMARYA 55-year-old man suffered an acute stroke, causing paralysis in the left upper and lower limbs. He intravenously transplanted the minimally manipulated human umbilical cord-derived MSCs (MM-UC-MSCs) twice with an 8-d interval. At 65 wk after transplantation, the patient returned to his previous occupation as a veterinarian with no adverse reactions.CONCLUSIONMM-UC-MSCs transplantation potentially treats patients who suffer from acute ischemic stroke. |
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Keywords: | Acute ischemic stroke Behavioral disorder Umbilical cord-derived mesenchymal stem cells Allogenic Cell therapy Minimal manipulation Case report |
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