Molecular modelling of a template substitute and monomers used in molecular imprinting for aflatoxin B1 micro-HPLC analysis |
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| Authors: | Miroslaw Wyszomirski Wojciech Prus |
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| Affiliation: | 1. University of Bielsko-Biala , Willowa 2, 43-309 , Bielsko-Biala , Poland mwyszomirski@ath.bielsko.pl;3. University of Bielsko-Biala , Willowa 2, 43-309 , Bielsko-Biala , Poland |
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| Abstract: | The preparation of molecularly imprinted polymers (MIPs) involves the polymerisation of functional monomers in the presence of template molecules. 5,7-Dimethoxycoumarin (DMC) was found to be a structural analogue for aflatoxin B1 (AB1) and serves as its substitute in a grafting solution for the MIP synthesis. It was found that both methacrylic acid and allylamine are functional monomers which could provide a similar binding towards AB1 and DMC. |
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| Keywords: | aflatoxin B1 molecular imprinting substitute molecular modelling |
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