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Molecular dynamics simulations of valveless pumping in a closed microfluidic tube-system
Authors:JS Hansen  JT Ottesen  A Lemarchand
Institution:1. Université Pierre et Marie Curie, Laboratoire de Physique Théorique de la Matière Condensée , C.N.R.S. U.M.R. 7600, 4, place Jussieu, 75252, Paris Cedex 05, France schmidt@zigzak.net;3. Roskilde University, Department of Mathematics and Physics , P.O. Box 260, 4000, Roskilde, Denmark;4. Université Pierre et Marie Curie, Laboratoire de Physique Théorique de la Matière Condensée , C.N.R.S. U.M.R. 7600, 4, place Jussieu, 75252, Paris Cedex 05, France
Abstract:In this paper, we study the flow which is generated by a valveless pumping mechanism in a closed micro-fluidic tube-system consisting of two tubes with different radii. This system has been investigated by Ottesen J. T. Ottesen, J. Math. Biol. 46, 309, (2003)] at a macroscopic level. We find that the results from the microscopic simulations qualitatively agree with the macroscopic results. Especially, it is shown that the direction of the flow changes with changing pumping frequency and the location of the pumping device. We study the local flow generated in the system and show that the stream velocities away from the pumping area can be modeled by a superposition of a plug flow and a zero-mean oscillatory flow.
Keywords:Valveless pumping  Nonequilibrium molecular dynamics  Moment current  Stream velocity  Oscillatory flow
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