Microbial production of (2R, 4R)-2,4-pentanediol by enatioselective reduction of acetylacetone and stereoinversion of 2,4-pentanediol |
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Authors: | Shuichi Matsumura Yoko Kawai Yoshinori Takahashi Kazunobu Toshima |
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Institution: | (1) Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, 223 Yokohama-shi, Japan |
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Abstract: | Summary (2R, 4R)-2,4-Pentanediol was obtained by the enatioselective reduction of acetylacetone (2,4-pentanedione) with the resting cells of methanol yeast,Candida boidinii KK912 (IFO 10574). (2R, 4R)-2,4-Pentanediol was also obtained by the stereoinversion of the isomeric mixture of 2,4-pentanediol. |
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