Chlamydial development is blocked in host cells transfected with <Emphasis Type="Italic">Chlamydophila caviae incA</Emphasis> |
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| Authors: | Damir?Alzhanov Jennifer?Barnes Dennis?E?Hruby Email author" target="_blank">Daniel?D?RockeyEmail author |
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| Institution: | (1) Department of Microbiology, Oregon State University, Corvallis, OR 97331-3804, USA;(2) Roche Diagnostics NZ Ltd, Molecular Diagnostics and Applied Science, PO Box 13941, Onehunga Auckland, New Zealand |
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| Abstract: | Background Chlamydiae produce a set of proteins, termed Inc proteins, that are localized to the inclusion membrane and exposed to the
host cell cytosol. Little information exists regarding the interaction of Inc proteins with the eukaryotic cell. To examine
these interactions, Vaccinia virus vectors and mammalian plasmid-based systems were used to express inc genes in mammalian cells. |
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