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Impact of gender on COPD expression in a real-life cohort
Authors:Nicolas Roche  Gaetan Deslée  Denis Caillaud  Graziella Brinchault  Isabelle Court-Fortune  Pascale Nesme-Meyer  Pascale Surpas  Roger Escamilla  Thierry Perez  Pascal Chanez  Christophe Pinet  Gilles Jebrak  Jean-Louis Paillasseur  Pierre-Régis Burgel
Abstract:Reports regarding gender-related differences in COPD expression have provided conflicting results. In the French Initiatives BPCO real-world cohort, which contained 688 patients (146 women) when data were extracted, women were matched with men (1:3 ratio: n = 107:275) on age (5-year intervals) and FEV1 (5% predicted intervals) and comparisons were performed using univariate logistic regressions. For a given age and level of airflow obstruction, women with COPD had higher BOD scores due to more pronounced dyspnea and lower BMI, suggesting worse prognosis, and were more likely to exhibit anxiety, suggesting the need for specific assessment and care.
Keywords:COPD   Gender   Clinical expression   Lung function   Age
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