Get ready to GO! A biologist's guide to the Gene Ontology |
| |
Authors: | Lomax Jane |
| |
Institution: | European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK. jane@ebi.ac.uk |
| |
Abstract: | The Gene Ontology (GO) project provides a controlled vocabulary to facilitate high-quality functional gene annotation for all species. Genes in biological databases are linked to GO terms, allowing biologists to ask questions about gene function in a manner independent of species. This tutorial provides an introduction for biologists to the GO resources and covers three of the most common methods of querying GO: by individual gene, by gene function and by using a list of genes. For the sake of brevity, the term 'gene' is used throughout this paper to refer to genes and their products (proteins and RNAs). GO annotations are always based on the characteristics of gene products, even though it may be the gene that is cited in the annotation.]. |
| |
Keywords: | Gene Ontology microarray gene annotation model organism database controlled vocabulary |
本文献已被 PubMed Oxford 等数据库收录! |
|