Effect of peripheral nerve on the neurite growth from retinal explants in culture |
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Authors: | Liu Li and So Kwokfai |
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Affiliation: | Liu Li and So KwokfaiShanghai Institute of Cell Biology,Academia Sinica,Shanghai,ChinaDepartment of Anatomy,University of Hong Kong,Hong Kong |
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Abstract: | The effect of peripheral nerve (PN) on neurite outgrowth from retinal explants of adult hamsters was examined. Cultures of retinal explants, and co-cultures of retinal explants and PN were performed using chick retinal basement membrane (BM) as substrate. The presence of PN increases the number and length of neurite outgrowth. In addition, a high proportion of neurites situated close to PN tend to grow towards it. Since there was no contact between retinal ex-plants and PN, we suggest that PN might secrete diffusible substances to attract the neurites to grow towards it. |
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Keywords: | retinal explants peripheral nerve tissue culture neurite outgrowth adult hamster. |
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