Isolation and screening of brittlestar-associated bacteria for antibacterial activity |
| |
Authors: | Strahl E D Dobson W E Lundie L L |
| |
Institution: | (1) Department of Biology, Appalachian State University, P.O. Box 32027, Boone, NC 28608-2027, USA, US |
| |
Abstract: | Many microbes associated with marine organisms have antimicrobial activity. We report the isolation of bacteria associated
with Amphipholis gracillima that have broad-spectrum antibacterial activity against a number of common bacterial strains. Fifty-eight isolates of bacilli
obtained from A. gracillima arm homogenates, from excised wound tissue, or from swabs of arm stumps exhibited 20–100% inhibition of one or more of 16
test bacteria at 35% salinity. Forty-one of the isolates were capable of 20–100% inhibition of one or more of 19 subject bacteria
at 10% salinity at 37°C. Three isolates, BE37, BE52, and BE53, exhibited the greatest range of antibacterial activity at both
10% and 35% salinity. Our results suggest that some of the bacteria associated with A. gracillima may provide the animal with chemical defenses against adverse bacterial infection. The water-soluble inhibitory chemicals
produced by the bacteria could potentially function as antimicrobial compounds against human pathogenic bacteria.
Received: 30 July 2001 / Accepted: 15 October 2001 |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|