Prostaglandin D2 is the major prostaglandin of arachidonic acid metabolism in rat bone marrow homogenate |
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| Authors: | Atsuko Kojima Masataka Shiraki Ryutaro Takahashi Hajime Orimo Ikuo Morita Sei-itsu Murota |
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| Affiliation: | 1. Department of Endocrinology, Tokyo Metropolitan Geriatric Hospital, Itabashi-ku, Tokyo-173, Japan;2. Department of Pharmacology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo-173, Japan |
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| Abstract: | Homogenate of bone marrow of male rat was incubated with 14C-arachidonic acid and with 14C-prostaglandin H2. The major prostaglandin produced during each incubation was prostaglandin D2, which was identified by thin-layer chromatography, autoradiography and chemical reduction. |
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