Release of L-glutamate from the excitatory nerve terminals of the crayfish neuromuscular junction.

Stimulation of the excitatory nerve to the crayfish neuromuscular junction resulted in an 87% increase of the rate of release of ¹⁴C-U-L-glutamate above resting levels. The extra release was abolished by stimulating the inhibitory fibers or by addition of GABA to the perfusing fluid. These results argue for the synaptic release of L-glutamate at this junction.