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Early combination disease-modifying antirheumatic drug therapy and tight disease control improve long-term radiologic outcome in patients with early rheumatoid arthritis: the 11-year results of the Finnish Rheumatoid Arthritis Combination Therapy trial |
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| Authors: | Vappu Rantalaiho Markku Korpela Leena Laasonen Hannu Kautiainen Salme Järvenpää Pekka Hannonen Marjatta Leirisalo-Repo Harri Blåfield Kari Puolakka Anna Karjalainen Timo Möttönen the FIN-RACo Trial Group |
| Affiliation: | 1.Department of Internal Medicine, Centre for Rheumatic Diseases,Tampere University Hospital,Tampere,Finland;2.Helsinki Medical Imaging Center,University of Helsinki,Helsinki,Finland;3.Orton Foundation,Helsinki,Finland;4.Medcare Foundation,??nekoski,Finland;5.Jyv?skyl? Central Hospital,Jyv?skyl?,Finland;6.Helsinki University Central Hospital,Helsinki,Finland;7.Sein?joki Central Hospital,Sein?joki,Finland;8.Lappeenranta Central Hospital,Lappeenranta,Finland;9.Oulu University Hospital,Oulu,Finland;10.Turku University Hospital,Turku,Finland |
| Abstract: | IntroductionEarly treatment of rheumatoid arthritis (RA) has been shown to retard the development of joint damage for a period of up to 5 years. The aim of this study was to evaluate the radiologic progression beyond that time in patients with early RA initially treated with a combination of three disease-modifying antirheumatic drugs (DMARDs) or a single DMARD. |
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