Differentiation of human multipotent dermal fibroblasts into islet-like cell clusters |
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Authors: | Dan Bi Fu Guo Chen Wen Jie Zhang Guang Dong Zhou Lei Cui Wei Liu Yilin Cao |
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Affiliation: | (1) Department of Plastic and Reconstructive Surgery, Shanghai 9thPeople's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Tissue Engineering, National Tissue Engineering Center of China, Shanghai, 200011, China |
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Abstract: | Background We have previously obtained a clonal population of cells from human foreskin that is able to differentiate into mesodermal, ectodermal and endodermal progenies. It is of great interest to know whether these cells could be further differentiated into functional insulin-producing cells. |
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