Chromosome-encoded beta-lactamases of Citrobacter diversus. Interaction with beta-iodopenicillanate and labelling of the active site. |
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| Authors: | G Amicosante A Oratore B Joris M Galleni J M Frère J Van Beeumen |
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| Affiliation: | Università degli Studi dell'Aquila Dipartimento di Scienze e Tecnologie Biomediche e di Biometria, Italy. |
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| Abstract: | Both forms of the chromosome-encoded beta-lactamase of Citrobacter diversus react with beta-iodopenicillanate at a rate characteristic of class A beta-lactamases. The active site of form I was labelled with the same reagent. The sequence of the peptide obtained after trypsin hydrolysis is identical with that of a peptide obtained in a similar manner from the chromosome-encoded beta-lactamase of Klebsiella pneumoniae. |
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