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Physiological responses to folate overproduction in <Emphasis Type="Italic">Lactobacillus plantarum</Emphasis> WCFS1

Authors:	Arno Wegkamp Astrid E Mars Magda Faijes Douwe Molenaar Ric CH de Vos Sebastian MJ Klaus Andrew D Hanson Willem M de Vos Eddy J Smid

Institution:	1.TI Food & Nutrition,Wageningen, Nieuwe Kanaal 9A,Wageningen,The Netherlands;2.NIZO food research,Kernhemseweg 2,Ede,The Netherlands;3.Plant Research International,Wageningen-UR,Wageningen,The Netherlands;4.Horticultural Sciences Department,University of Florida,Florida,USA;5.Institut Químic de Sarrià,Universitat Ramon Llull,Barcelona,Spain;6.Agrotechnology &,Food Sciences group,Wageningen,The Netherlands;7.Laboratory of Microbiology,Wageningen University,Wageningen,The Netherlands;8.Laboratory of Food Microbiology,Wageningen University,Wageningen,The Netherlands;9.Securetec Detektions-Systeme AG,Eugen-S?nger-Ring 1,Brunnthal,Germany

Abstract:	Background Using a functional genomics approach we addressed the impact of folate overproduction on metabolite formation and gene expression in Lactobacillus plantarum WCFS1. We focused specifically on the mechanism that reduces growth rates in folate-overproducing cells.

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