Effect of boronic acids on antifreeze proteins |
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Authors: | R. E. Feeney D. T. Osuga Yin Yeh |
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Affiliation: | (1) Department of Food Science and Technology, University of California, 95616 Davis, California;(2) Protein Structure Laboratory, HSRL, University of California, 95616 Davis, California;(3) Department of Applied Science, University of California, 95616 Davis, California |
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Abstract: | The activity of antifreeze glycoprotein from the blood serum ofBoreagadus saida was strongly inhibited by ions of organic boronic acids as well as by borate. The activity of nonglycoprotein from the blood serum ofPseudopleuronectus americanus, however, was not similarly inhibited. The inhibition by borate is thus specific for molecules with the carbohydrate moiety. |
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Keywords: | Antifree proteins borate inhibition by glycoprotein |
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