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两种检测抗生素S632A对Vero细胞毒性作用方法的比较
引用本文:何健民,石立莹,李晓眠,李电东,刘琼岩. 两种检测抗生素S632A对Vero细胞毒性作用方法的比较[J]. 微生物学杂志, 2006, 26(1): 33-35
作者姓名:何健民  石立莹  李晓眠  李电东  刘琼岩
作者单位:1. 天津医科大学,微生物教研室,天津,300070
2. 中国协和医科大学,中国医学科学院医药生物技术研究所,北京,100050
摘    要:为检测S632A对细胞的毒性作用,比较了CPE法及MTT法检测其效果,结果可见,2种方法均可证明S632A对细胞的毒性较低,MTT法比CPE法敏感性高。

关 键 词:MTT法  CPE法  TI(治疗指数)
文章编号:1005-7021(2006)01-0033-03
修稿时间:2004-05-12

Comparison of Two Antibiotics S632A Toxicity Testing against Vero Cell
HE Jian-min,SHI Li-ying,LI Xiao-mian,LI Dian-dong,LIU Qiong-yan. Comparison of Two Antibiotics S632A Toxicity Testing against Vero Cell[J]. Journal of Microbiology, 2006, 26(1): 33-35
Authors:HE Jian-min  SHI Li-ying  LI Xiao-mian  LI Dian-dong  LIU Qiong-yan
Affiliation:1.Teach.& Res.Sect.of Microbiol.Tianjin Med.Univ.Tianjin 300070; 2.Inst.of Med.Biotech.China Acad.of Med.Sci.China Concorde Med.Univ.Beijing 10050
Abstract:Cell toxicity of antibiotics S632A testing methods were compared by MTT and CPE assays.It was proved that toxicity of S632A was low to cell.And it was found that MTT assay is higher than CPE in the sensitivity.
Keywords:MTT  CPE  TI(therapeutic index)
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