| 中国汉族人群间-α-胰蛋白酶抑制因子(ITI)的遗传多态性 |
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| 引用本文： | 侯一平,芶清,吴梅筠.中国汉族人群间-α-胰蛋白酶抑制因子(ITI)的遗传多态性[J].遗传学报,1993(5). |
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| 作者姓名： | 侯一平 芶清 吴梅筠 |
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| 作者单位： | 华西医科大学法医系，华西医科大学法医系，华西医科大学法医系 成都 610044，成都 610044，成都 610044 |
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| 摘 要： | 我们建立了测定间-α-胰蛋白酶抑制因子遗传表型的聚丙烯酰胺凝胶等电聚焦免疫固定技术,应用这种方法对居住在成都地区的汉族群体进行了群体研究和家系调查,结果表明中国汉族人群间-α-胰蛋白酶抑制因子具有遗传多态性,它有希望成为法医血液遗传学新的遗传标记。
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| 关 键 词： | 间-α-胰蛋白酶抑制因子 遗传多态性 等电聚焦 |
Genetic Polymorphism of Inter-Alpha-Trypsin-Inhibitor (ITI) in a Han Population in China |
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| Hou Yiping Gou Qing Wu Meiyun.Genetic Polymorphism of Inter-Alpha-Trypsin-Inhibitor (ITI) in a Han Population in China[J].Journal of Genetics and Genomics,1993(5). |
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| Authors: | Hou Yiping Gou Qing Wu Meiyun |
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| Abstract: | Phenotypes of inter-alpha-trypsin-inhibitor (ITI) have been determined by isoelectric focusing on the polyacrylamide gel followed by immunofixation. The phenotype frequencies of ITI in the Han population in Chengdu, China were investigated using this method. In addition, family studies have been conducted in 21 families. The results showed that the ITI was polymorphic in the Han population in Chengdu. The allele frequencies were as follows: ITI*1 = 0.5763, ITI*2 = 0.4107, ITI*3 = 0.0130. It was obvious that the ITI is a new and promising genetic marker which can be used in the field of forensic haematogenetics. |
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| Keywords: | Inter-alpha-trypsin-inhibitor Genetic polymorphism Isoelectric focasing |
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