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Affinity Map of Bromodomain Protein 4 (BRD4) Interactions with the Histone H4 Tail and the Small Molecule Inhibitor JQ1 |
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| Authors: | Marie Jung Martin Philpott Susanne Müller Jessica Schulze Volker Badock Uwe Ebersp?cher Dieter Moosmayer Benjamin Bader Norbert Schmees Amaury Fernández-Montalván Bernard Haendler |
| Affiliation: | From the ‡Global Drug Discovery, Bayer HealthCare, 13353 Berlin, Germany.;the §Institute of Chemistry and Biochemistry, Free University, 14195 Berlin, Germany, and ;¶Structural Genomics Consortium and Target Discovery Institute, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom |
| Abstract: | |
| Keywords: | Anticancer Drug Cancer Therapy Chromatin Histones Mutant Acetylation BET Family BRD4 Bromodomain |