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Dimerization of Cadherin-11 involves multi-site coupled unfolding and strand swapping
Institution:1. Department of Biochemistry and Molecular Biophysics, Columbia University Irving Medical Center, 701 West 168th Street, New York, NY 10032, USA;2. Zuckerman Institute, Columbia University, 3227 Broadway, New York, NY 10027, USA;3. Department of Systems Biology, Columbia University Irving Medical Center, 1130 St. Nicholas Avenue, New York, NY 10032, USA;4. Department of Medicine, Columbia University Irving Medical Center, 630 West 168th Street, New York, NY 10032, USA
Abstract:
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  • Keywords:adherens junctions  cell adhesion  CEST  chemical exchange  CPMG relaxation dispersion  domain-swapping  high-pressure NMR  protein dynamics and kinetics  type II cadherin
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