Sodium Zeolite A Supplementation and Its Impact on the Skeleton of Dairy Calves |
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Authors: | K K Turner B D Nielsen C I O’Connor-Robison D S Rosenstein B P Marks F H Nielsen M W Orth |
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Institution: | (1) Department of Animal Science, Michigan State University, East Lansing, 48824, USA;(2) Department of Large Animal Clinical Science, Michigan State University, East Lansing, 48824, USA;(3) Department of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, 48824, USA;(4) US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, 58202, USA;(5) E.L. Rhodes Center, Animal and Dairy Science Department, The University of Georgia, Athens, GA 30602, USA |
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Abstract: | Twenty calves were placed on study at 3 days of age and were placed according to birth order into one of two groups: SS, which
received 0.05% BW sodium zeolite A (SZA) added to their milk replacer, and CO, which received only milk replacer. Blood samples
were taken on days 0, 30, and 60 for osteocalcin (OC) and deoxypyridinoline (DPD) analysis. On day 60, the calves were euthanized,
and synovial fluid, articular cartilage, and both fused metacarpals were collected for bone quality analyses such as architecture
and mechanical properties, mineral composition, and glycosaminoglycan concentration. There were no differences in OC concentrations
because of treatment (p = 0.12), and CO calves had lower DPD concentrations than SS calves (p = 0.01), but the OC-to-DPD ratio was not different between treatments (p = 0.98). No differences in bone architecture or mechanical properties were detected. SZA supplementation increased cortical
bone (p = 0.0002) and articular cartilage (p = 0.05) aluminum content. Glycosaminoglycan concentrations were not different in synovial fluid or cartilage. Supplementation
of SZA appeared to alter the rate of bone turnover without altering bone strength. Aluminum concentrations in the bone and
cartilage increased, which may be a concern, although the long-term consequences of such remain to be determined. |
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Keywords: | Sodium zeolite A Skeleton Silicon Aluminum Bone Mineral Calf |
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