SAR studies of gymnasterkoreayne derivatives with cancer chemopreventive activities |
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| Authors: | Shin Dongyun Yang Jung-Eun Lee Saet Byoul Nho Chu Won |
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| Affiliation: | Life/Health Division, Korea Institute of Science and Technology (KIST), Seongbuk-Gu, Seoul, Republic of Korea. dyshin21@kist.re.kr |
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| Abstract: | We synthesized diyne triols based on gymnasterkoreayne and evaluated their cancer chemopreventive activities in terms of the chemopreventive index (CI) to reveal the structure-activity relationship, and discovered more active compounds than natural diynes. |
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