Novel conserved assembly factor of the bacterial flagellum |
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| Authors: | Titz Björn Rajagopala Seesandra V Ester Claudia Häuser Roman Uetz Peter |
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| Institution: | Institute of Genetics, Forschungszentrum Karlsruhe, Box 3640, D-76021 Karlsruhe, Germany. |
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| Abstract: | TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum. |
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