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CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation |
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| Authors: | Cynthia M. Quintero Kristian B. Laursen Nigel P. Mongan Minkui Luo Lorraine J. Gudas |
| Affiliation: | 1. Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY, USA;2. Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA;3. Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Loughborough, UK;4. Weill Cornell Graduate School of Medical Sciences—Pharmacology Program, Weill Cornell Medical College of Cornell University, New York, NY, USA |
| Abstract: | |
| Keywords: | CARM1 retinoic acid NR2F1/Coup-TF1 CRABP2 epigenetic marks ESCs Embryonic stem cells RA retinoic acid RAR retinoic acid receptor NR nuclear receptor RXR retinoid X receptor RAREs retinoic acid-responsive elements PRC2 polycomb repressive complex 2 PRMTs protein arginine methyltransferases CARM1 coactivator-associated arginine methyltransferase 1 shCtl shRNA control me-PABP1 methylated-poly(A)-binding protein 1 ChIP chromatin immunoprecipitation |
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