From Atoms to Cells: Using Mesoscale Landscapes to Construct Visual Narratives |
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| Authors: | David S. Goodsell Margaret A. Franzen Tim Herman |
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| Affiliation: | 1. Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA;2. RCSB Protein Data Bank & Center for Integrative Proteomics Research, Rutgers State University, Piscataway, NJ 08854, USA;3. Center for BioMolecular Modeling, Milwaukee School of Engineering, Milwaukee, WI 53202, USA |
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| Abstract: | Modeling and visualization of the cellular mesoscale, bridging the nanometer scale of molecules to the micrometer scale of cells, is being studied by an integrative approach. Data from structural biology, proteomics, and microscopy are combined to simulate the molecular structure of living cells. These cellular landscapes are used as research tools for hypothesis generation and testing, and to present visual narratives of the cellular context of molecular biology for dissemination, education, and outreach. |
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| Keywords: | cellular mesoscale mesoscale modeling molecular graphics science education integrative structural biology |
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