|
|||||
|
|
Sarcoptes scabiei var. hominis: Three-dimensional structure of a female imago and crusted scabies lesions by X-ray micro-CT |
|
| Authors: | Hideyuki Yoshimura Takuji Ohigashi Masayuki Uesugi Kentaro Uesugi Ryuichi Nakamura Kunio Shinohara |
| Affiliation: | a Department of Physics, Meiji University, 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Japan b JASRI/SPring-8, 1-1-1, Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198, Japan c Research Organization of Science & Engineering, Ritsumeikan University, 1-1-1 Noji Higashi, Kusatsu 525-8577, Japan d Department of Earth and Space Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan e Higashikawa Dermatology Office, 1-1-16 Ouji-cho, Nada-ku, Kobe 657-0838, Japan f Nakamura Dermatology Office, 1-5-6 Arata-cho, Hyogo-ku, Kobe 653-0032, Japan g Mori Clinic (Dermatology), 1-1-20 Funadera-dori, Nada-ku, Kobe 657-0842, Japan h Advanced Research Institute for Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan |
| Abstract: | The three-dimensional structure of scabies mites (Sarcoptes scabiei var. hominis) and keratin layers affected by crusted scabies lesions were obtained using X-ray computed tomography at sub-micrometer and micrometer resolution, respectively (X-ray micro-CT). Clear three-dimensional images including internal structure of scabies mites were obtained. Utilizing reconstructed micro-CT data, the sections of the capitulum (head part), digestive organs, and legs are shown. The reconstructed capitulum shows a jaw-like structure capable of penetrating the keratin layer of the skin. The tip of the forelegs of female scabies mites has a flat disk structure that may be used to grasp the skin surface. The keratin layer of a crusted scabies lesion spontaneously exfoliated from a patient was also reconstructed by the X-ray micro-CT technique. Extracted sections from CT data revealed a network structure of tunnels made by scabies mites with numerous larvae and eggs inside the tunnels. |
| Keywords: | Scabies mites Crusted scabies Keratin layer Mites tunnel X-ray micro-CT Internal structure Synchrotron radiation |
| 本文献已被 ScienceDirect 等数据库收录！ | |