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Acanthamoeba castellanii: High antibody prevalence in racially and ethnically diverse populations
Authors:Neil Brindley  Abdul Matin
Institution:a Department of Biology, Lambeth College, UK
b School of Biological and Chemical Sciences, Birkbeck College, University of London, UK
c School of Veterinary Medicine and Science, University of Nottingham, College Road, Sutton Bonington, Leicestershire, LE12 5RD, England, UK
Abstract:Acanthamoeba is an opportunistic protozoan pathogen that can produce keratitis and rare but fatal encephalitis. In the present study, we examined secretory IgA antibody to Acanthamoeba castellanii of the T4 genotype in mucosal secretions from 114 individuals of 37 countries, inhabitants and/or visitors, aged 16-65 years in London, UK. Acanthamoeba antibody prevalence rate was more than 85%, without any significant differences between males (86.2%) and females (89.2%). Some epidemiological factors contributing to the high prevalence of antibody to Acanthamoeba in surveyed population are discussed further.
Keywords:Acanthamoeba  Epidemiology  Prevalence  Protozoa
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