| 鞘氨醇-1磷酸盐的生理功能研究进展 |
| |
| 作者姓名： | Duan HF Wang LS Wu C |
| |
| 作者单位： | 北京放射医学研究所,北京,100850 |
| |
| 摘 要： | 鞘氨醇－1磷酸盐（SPP）是神经鞘磷脂代谢产生的一种有生物活性的脂类,在细胞的多种生物学过程中起着重要的作用。包括细胞的增殖、存活、细胞骨架改变、迁移、血管发生、创伤愈合和胚胎发育等。本文综述了SPP在细胞生物功能调节和信号转导中的作用。
|
| 关 键 词： | 鞘氨醇－1磷酸盐 内皮分化基因 血管发生 |
Progress in the study of physiological function of sphingosine 1-phosphate |
| |
| Duan HF,Wang LS,Wu C.Progress in the study of physiological function of sphingosine 1-phosphate[J].Progress in Physiological Sciences,2003,34(1):16-20. |
| |
| Authors: | Duan Hai-Feng Wang Li-Sheng Wu Chutse |
| |
| Institution: | Beijing Institute of Radiation Medicine, Beijing 100850. |
| |
| Abstract: | Sphingosine 1 phosphate, a bioactive sphingolipid produced from the metabolism of sphingo myelin, play important roles in diverse biological process, including cell proliferation, survival, cytoskeleton changes, migration, angiogenesis, wound healing and embryonic development. Here we review the role of sphingosine 1 phosphate in cell biological function regulation and signal transduction. |
| |
| Keywords: | Sphingosine 1phosphate Endothelial differentiation gene Angiogenesis |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
|
