| 肝细胞生长因子的分子生物学研究 |
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| 引用本文： | 俞水亮, 杨复华,. 肝细胞生长因子的分子生物学研究[J]. 生物工程学报, 2002, 18(1): 1-4 |
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| 作者姓名： | 俞水亮 杨复华 |
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| 作者单位： | 武汉大学生命科学院,武汉,430072 |
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| 摘 要： | 肝细胞生长因子 (HGF)是一种多功能细胞因子 ,其分子为异二聚体糖蛋白 ,有NK1,NK2 ,NK4三个变种。HGF启动子的结构很复杂 ,其表达受多种因素和调控元件的调节。因HGF在体内有重要作用 ,HGF的基因工程表达和基因治疗正在研究中
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| 关 键 词： | 肝细胞生长因子（HGF） 基因表达 基因工程 |
| 文章编号： | 1000-3061(2002)01-0001-04 |
| 修稿时间： | 2001-05-21 |
Molecular Biological Progress of Hepatocyte Growth Factor (HGF) |
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| YU Shui-Liang YANG Fu-Hua. Molecular Biological Progress of Hepatocyte Growth Factor (HGF)[J]. Chinese journal of biotechnology, 2002, 18(1): 1-4 |
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| Authors: | YU Shui-Liang YANG Fu-Hua |
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| Affiliation: | College of Life Science, Wuhan University, Wuhan 430072, China. |
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| Abstract: | Hepatocyte growth factor (HGF) is a multifunctional growth factor which is a heterodimeric glycoprotein molecule. There are three truncated HGF variants:NK1,NK2,NK4.The structure of the promoter of HGF is very complicated, and the expression of HGF is regulated by various factors and regulatory elements. Because of the importance of HGF to human body, the genetic engineering expression and gene therapy investigation of HGF are being done. |
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| Keywords: | hepatocyte growth factor (HGF) gene expression genetic engineering |
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