Exclusion of the gelsolin gene on 9q32-34 as the cause of familial lattice corneal dystrophy type I. |
| |
| Authors: | A Wiens S Marles J Safneck D J Kwiatkowski C P Maury T Zelinski S Philipps M B Ekins and C R Greenberg |
| |
| Institution: | Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada. |
| |
| Abstract: | Familial lattice corneal dystrophy type I (LCD1) is a localized form of inherited amyloidosis limited to the corneal stroma. Recently the Finnish form of hereditary amyloidosis with lattice corneal dystrophy has been shown to be due to a mutation in the gelsolin gene (G654----A; Asp187----Asn). In this paper we exclude the gelsolin gene as the cause of the autosomal dominant form of isolated LCD1. |
| |
| Keywords: | |
|
