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Target DNA recognition and cleavage by a reconstituted Type I-G CRISPR-Cas immune effector complex |
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| Authors: | Majumdar Sonali Ligon Marianne Skinner William Colby Terns Rebecca M. Terns Michael P. |
| Affiliation: | 1.Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA ;2.Department of Genetics, University of Georgia, Athens, GA, 30602, USA ;3.Department of Microbiology, University of Georgia, Athens, GA, 30602, USA ;4.Department of Biology, University of Georgia, Athens, GA, 30602, USA ; |
| Abstract: | Extremophiles - CRISPR-Cas immune systems defend prokaryotes against viruses and plasmids. CRISPR RNAs (crRNAs) associate with various CRISPR-associated (Cas) protein modules to form structurally... |
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